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Comparison of rapamycin schedules in mice on high-fat diet

At a wide range of doses, rapamycin extends life span in mice. It was shown that intraperitoneal injections (i.p.) of rapamycin prevent weight gain in mice on high-fat diet (HFD). We further investigated the effect of rapamycin on weight gain in female C57BL/6 mice on HFD started at the age of 7.5 m...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Leontieva, Olga V, Paszkiewicz, Geraldine M, Blagosklonny, Mikhail V
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614913/
https://ncbi.nlm.nih.gov/pubmed/25485580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.970491
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