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Weekly administration of rapamycin improves survival and biomarkers in obese male mice on high-fat diet
Recent discoveries have revealed the key role of mTOR (target of rapamycin) in aging. Furthermore, rapamycin extends lifespan in mice, especially in female mice. Here, we treated obese male mice on high-fat diet with rapamycin given intermittently: either weekly (once a week) or alternating bi-weekl...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326934/ https://ncbi.nlm.nih.gov/pubmed/24655348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12211 |
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