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Weekly administration of rapamycin improves survival and biomarkers in obese male mice on high-fat diet

Recent discoveries have revealed the key role of mTOR (target of rapamycin) in aging. Furthermore, rapamycin extends lifespan in mice, especially in female mice. Here, we treated obese male mice on high-fat diet with rapamycin given intermittently: either weekly (once a week) or alternating bi-weekl...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Aging Cell
Asıl Yazarlar: Leontieva, Olga V, Paszkiewicz, Geraldine M, Blagosklonny, Mikhail V
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326934/
https://ncbi.nlm.nih.gov/pubmed/24655348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12211
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