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Fasting levels of hepatic p-S6 are increased in old mice

TOR is involved in aging in a wide range of species from yeast to mammals. Here we show that, after overnight fasting, mTOR activity is higher in the livers of 28 months old female mice compared with middle-aged mice. Taken together with previous reports, our data predict that the life-extending eff...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Leontieva, Olga V, Paszkiewicz, Geraldine M, Blagosklonny, Mikhail V
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612665/
https://ncbi.nlm.nih.gov/pubmed/25486351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.949150
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