Spatio-temporal regulation of the human licensing factor Cdc6 in replication and mitosis

To maintain genome stability, the thousands of replication origins of mammalian genomes must only initiate replication once per cell cycle. This is achieved by a strict temporal separation of ongoing replication in S phase, and the formation of pre-replicative complexes in the preceding G1 phase, wh...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Kalfalah, Faiza M, Berg, Elke, Christensen, Morten O, Linka, René M, Dirks, Wilhelm G, Boege, Fritz, Mielke, Christian
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
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Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614858/
https://ncbi.nlm.nih.gov/pubmed/25875233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2014.1000182
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