Spatio-temporal regulation of the human licensing factor Cdc6 in replication and mitosis

To maintain genome stability, the thousands of replication origins of mammalian genomes must only initiate replication once per cell cycle. This is achieved by a strict temporal separation of ongoing replication in S phase, and the formation of pre-replicative complexes in the preceding G1 phase, wh...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Kalfalah, Faiza M, Berg, Elke, Christensen, Morten O, Linka, René M, Dirks, Wilhelm G, Boege, Fritz, Mielke, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614858/
https://ncbi.nlm.nih.gov/pubmed/25875233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2014.1000182
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