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The checkpoint clamp protein Rad9 facilitates DNA-end resection and prevents alternative non-homologous end joining

DNA damage activates the cell cycle checkpoint to regulate cell cycle progression. The checkpoint clamp (Rad9-Hus1-Rad1 complex) is recruited to damage sites, and is required for checkpoint activation. While functions of the checkpoint clamp in checkpoint activation have been well studied, its funct...

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Vydáno v:Cell Cycle
Hlavní autoři: Tsai, Feng-Ling, Kai, Mihoko
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614839/
https://ncbi.nlm.nih.gov/pubmed/25485590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.958386
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