Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells

Approximately 25% of breast cancers overexpress and depend on the receptor tyrosine kinase ERBB2, one of 4 ERBB family members. Targeted therapies directed against ERBB2 have been developed and used clinically, but many patients continue to develop resistance to such therapies. Although much effort...

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Publicado en:Cell Cycle
Main Authors: Canfield, Kaleigh, Li, Jiaqi, Wilkins, Owen M., Morrison, Meghan M, Ung, Matthew, Wells, Wendy, Williams, Charlotte R., Liby, Karen T, Vullhorst, Detlef, Buonanno, Andres, Hu, Huizhong, Schiff, Rachel, Cook, Rebecca S, Kurokawa, Manabu
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
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Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614407/
https://ncbi.nlm.nih.gov/pubmed/25590338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.994966
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