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Inverse association between MDM2 and HUWE1 protein expression levels in human breast cancer and liposarcoma
The ubiquitin E3 ligase MDM2 is best known for its ability to suppress the tumor suppressor p53. However, MDM2 also targets other proteins for proteasomal degradation and accumulating evidence strongly suggests p53-independent roles of MDM2 in cancer. We previously reported that MDM2 promotes degrad...
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| Udgivet i: | Int J Clin Exp Pathol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5782804/ https://ncbi.nlm.nih.gov/pubmed/29375730 |
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