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X-Linked Huwe1 Is Essential for Oocyte Maturation and Preimplantation Embryo Development
Summary: HUWE1 is a HECT-domain ubiquitin E3 ligase expressed in various tissues. Although HUWE1 is known to promote degradation of the tumor suppressor p53, given a growing list of its substrates, in vivo functions of HUWE1 remain elusive. Here, we investigated the role of HUWE1 in the female repro...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2020-09-01
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| Serija: | iScience |
| Teme: | |
| Online dostop: | http://www.sciencedirect.com/science/article/pii/S258900422030715X |
| Oznake: |
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