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X-Linked Huwe1 Is Essential for Oocyte Maturation and Preimplantation Embryo Development

Summary: HUWE1 is a HECT-domain ubiquitin E3 ligase expressed in various tissues. Although HUWE1 is known to promote degradation of the tumor suppressor p53, given a growing list of its substrates, in vivo functions of HUWE1 remain elusive. Here, we investigated the role of HUWE1 in the female repro...

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Detaylı Bibliyografya
Asıl Yazarlar: Alaa A. Eisa, Scott Bang, Katherine J. Crawford, Emily M. Murphy, William W. Feng, Souvik Dey, Wendy Wells, Ning Kon, Wei Gu, Lisa M. Mehlmann, Srinivasan Vijayaraghavan, Manabu Kurokawa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020-09-01
Seri Bilgileri:iScience
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S258900422030715X
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