CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies

Although it is established that fatty acid (FA) synthesis supports anabolic growth in cancer, the role of exogenous FA uptake remains elusive. Here we show that, during acquisition of resistance to HER2 inhibition, metabolic rewiring of breast cancer cells favors reliance on exogenous FA uptake over...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Feng, William W., Wilkins, Owen, Bang, Scott, Ung, Matthew, Li, Jiaqi, An, Jennifer, del Genio, Carmen, Canfield, Kaleigh, DiRenzo, James, Wells, Wendy, Gaur, Arti, Robey, R. Brooks, Guo, Jessie Yanxiang, Powles, Ryan L., Sotiriou, Christos, Pusztai, Lajos, Febbraio, Maria, Cheng, Chao, Kinlaw, William B., Kurokawa, Manabu
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938262/
https://ncbi.nlm.nih.gov/pubmed/31825825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados