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NMDA receptors regulate Neuregulin 2 binding to ER-PM junctions and ectodomain release
Unprocessed pro-Neuregulin 2 (pro-NRG2) accumulates on neuronal cell bodies at junctions between the endoplasmic reticulum and plasma membrane (ER-PM junctions). NMDA receptors (NMDARs) trigger NRG2 ectodomain shedding from these sites followed by activation of ErbB4 receptor tyrosine kinases, and E...
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| Veröffentlicht in: | Mol Neurobiol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8262096/ https://ncbi.nlm.nih.gov/pubmed/31240601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01659-w |
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