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NMDA receptors regulate Neuregulin 2 binding to ER-PM junctions and ectodomain release

Unprocessed pro-Neuregulin 2 (pro-NRG2) accumulates on neuronal cell bodies at junctions between the endoplasmic reticulum and plasma membrane (ER-PM junctions). NMDA receptors (NMDARs) trigger NRG2 ectodomain shedding from these sites followed by activation of ErbB4 receptor tyrosine kinases, and E...

詳細記述

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書誌詳細
出版年:Mol Neurobiol
主要な著者: Vullhorst, Detlef, Buonanno, Andres
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262096/
https://ncbi.nlm.nih.gov/pubmed/31240601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01659-w
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