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Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors
Neuregulin-1 (NRG-1) is genetically linked with schizophrenia, a neurodevelopmental cognitive disorder characterized by imbalances in glutamatergic and dopaminergic function. NRG-1 regulates numerous neurodevelopmental processes and, in the adult, suppresses or reverses long-term potentiation (LTP)...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2563131/ https://ncbi.nlm.nih.gov/pubmed/18832154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805722105 |
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