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Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors

Neuregulin-1 (NRG-1) is genetically linked with schizophrenia, a neurodevelopmental cognitive disorder characterized by imbalances in glutamatergic and dopaminergic function. NRG-1 regulates numerous neurodevelopmental processes and, in the adult, suppresses or reverses long-term potentiation (LTP)...

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Detalles Bibliográficos
Main Authors: Kwon, Oh Bin, Paredes, Daniel, Gonzalez, Carmen M., Neddens, Jörg, Hernandez, Luis, Vullhorst, Detlef, Buonanno, Andres
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563131/
https://ncbi.nlm.nih.gov/pubmed/18832154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805722105
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