Neuregulin-1 Reverses Long-Term Potentiation at CA1 Hippocampal Synapses

Neuregulin-1 (NRG-1) has been identified genetically as a schizophrenia susceptibility gene, but its function in the adult brain is unknown. Here, we show that NRG-1β does not affect basal synaptic transmission but reverses long-term potentiation (LTP) at hippocampal Schaffer collateral→CA1 synapses...

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Publicat a:J Neurosci
Autors principals: Kwon, Oh-Bin, Longart, Marines, Vullhorst, Detlef, Hoffman, Dax A., Buonanno, Andres
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2005
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725708/
https://ncbi.nlm.nih.gov/pubmed/16221846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2100-05.2005
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