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The Importance of the NRG-1/ErbB4 Pathway for Synaptic Plasticity and Behaviors Associated with Psychiatric Disorders

Neuregulin 1 (NRG-1) and its receptor ErbB4 have emerged as biologically plausible schizophrenia risk factors, modulators of GABAergic and dopaminergic neurotransmission, and as potent regulators of glutamatergic synaptic plasticity. NRG-1 acutely depotentiates LTP in hippocampal slices, and blockin...

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Autori principali: Shamir, Alon, Kwon, Oh-Bin, Karavanova, Irina, Vullhorst, Detlef, Leiva-Salcedo, Elias, Janssen, Megan J., Buonanno, Andres
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302154/
https://ncbi.nlm.nih.gov/pubmed/22378872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1899-11.2012
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