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Computational evidence that fast translation speed can increase the probability of cotranslational protein folding

Translation speed can affect the cotranslational folding of nascent peptide. Experimental observations have indicated that slowing down translation rates of codons can increase the probability of protein cotranslational folding. Recently, a kinetic modeling indicates that fast translation can also i...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wang, Ercheng, Wang, Jun, Chen, Changjun, Xiao, Yi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614103/
https://ncbi.nlm.nih.gov/pubmed/26486723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15316
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