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SUMOylation of the C-terminal domain of DNA topoisomerase IIα regulates the centromeric localization of Claspin
DNA topoisomerase II (TopoII) regulates DNA topology by its strand passaging reaction, which is required for genome maintenance by resolving tangled genomic DNA. In addition, TopoII contributes to the structural integrity of mitotic chromosomes and to the activation of cell cycle checkpoints in mito...
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| Publicado en: | Cell Cycle |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4614044/ https://ncbi.nlm.nih.gov/pubmed/26131587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1066537 |
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