Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations

Telomerase reactivation and immortalization are critical for human carcinoma progression. However, little is known about the mechanisms controlling this crucial step, due in part to the paucity of experimentally tractable model systems that can examine human epithelial cell immortalization as it mig...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Garbe, James C, Vrba, Lukas, Sputova, Klara, Fuchs, Laura, Novak, Petr, Brothman, Arthur R, Jackson, Mark, Chin, Koei, LaBarge, Mark A, Watts, George, Futscher, Bernard W, Stampfer, Martha R
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613853/
https://ncbi.nlm.nih.gov/pubmed/25485586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.954456
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados