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Exome-wide Mutation Profile in Benzo[a]pyrene-derived Post-stasis and Immortal Human Mammary Epithelial Cells

Genetic mutations are known to drive cancer progression and certain tumors have mutation signatures that reflect exposures to environmental carcinogens. Benzo[a]pyrene (BaP) has a known mutation signature and has proven capable of inducing changes to DNA sequence that drives normal pre-stasis human...

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Detalhes bibliográficos
Publicado no:Mutat Res Genet Toxicol Environ Mutagen
Main Authors: Severson, Paul L., Vrba, Lukas, Stampfer, Martha R., Futscher, Bernard W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250937/
https://ncbi.nlm.nih.gov/pubmed/25435355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2014.10.011
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