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Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth
Aberrant activation of SHH pathway is a major cause of medulloblastoma (MB), the most frequent brain malignancy of the childhood. A few Hedgehog inhibitors, all antagonizing the membrane transducer Smo, have been approved or are under clinical trials for the treatment of human MB. However, the effic...
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| Gepubliceerd in: | Cell Cycle |
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| Hoofdauteurs: | , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613849/ https://ncbi.nlm.nih.gov/pubmed/25485584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.952973 |
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