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Antitumor Efficacy of Colon-Specific HPMA Copolymer/9-Aminocamptothecin Conjugates in Mice Bearing Human-Colon Carcinoma Xenografts
The antitumor activity of a colon-specific N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer – 9-aminocamptothecin (9-AC) conjugate (P-9-AC) was assessed in orthotopic and subcutaneous animal (HT29 xenograft) tumor models. P-9-AC treatment of mice bearing orthotopic colon tumors, with a dose of 3 m...
Tallennettuna:
| Julkaisussa: | Macromol Biosci |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613765/ https://ncbi.nlm.nih.gov/pubmed/19685500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.200900147 |
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