Llwytho...

Biological Activity of Anti-CD20 Multivalent HPMA Copolymer-Fab’ Conjugates

High-molecular-weight, branched N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers were synthesized and conjugated with Fab’ fragments of the anti-CD20 antibody, 1F5. This produced multivalent conjugates with varying valency (amount of Fab’ per macromolecule) targeted to the B-cell antigen CD20. Th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Johnson, Russell N., Kopečková, Pavla, Kopeček, Jindřich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299848/
https://ncbi.nlm.nih.gov/pubmed/22288884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm201656k
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