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Divergent Inhibitor Susceptibility among Airway Lumen-Accessible Tryptic Proteases

Tryptic serine proteases of bronchial epithelium regulate ion flux, barrier integrity, and allergic inflammation. Inhibition of some of these proteases is a strategy to improve mucociliary function in cystic fibrosis and asthmatic inflammation. Several inhibitors have been tested in pre-clinical ani...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nimishakavi, Shilpa, Raymond, Wilfred W., Gruenert, Dieter C., Caughey, George H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612780/
https://ncbi.nlm.nih.gov/pubmed/26485396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141169
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