Cleavage of Influenza Virus Hemagglutinin by Airway Proteases TMPRSS2 and HAT Differs in Subcellular Localization and Susceptibility to Protease Inhibitors

Proteolytic cleavage of the influenza virus surface glycoprotein hemagglutinin (HA) by host cell proteases is crucial for infectivity and virus spread. The proteases HAT (human airway trypsin-like protease) and TMPRSS2 (transmembrane protease serine S1 member 2) known to be present in the human airw...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Böttcher-Friebertshäuser, Eva, Freuer, Catharina, Sielaff, Frank, Schmidt, Sarah, Eickmann, Markus, Uhlendorff, Jennifer, Steinmetzer, Torsten, Klenk, Hans-Dieter, Garten, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876594/
https://ncbi.nlm.nih.gov/pubmed/20237084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00140-10
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados