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Proteolytic Activation of Influenza Viruses by Serine Proteases TMPRSS2 and HAT from Human Airway Epithelium

Host cell proteases that cleave the hemagglutinin (HA) of influenza viruses in the human respiratory tract are still not identified. Here we cloned two human type II transmembrane serine proteases with known airway localization, TMPRSS2 and HAT, into mammalian expression vector. Cotransfection of ma...

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書誌詳細
主要な著者: Böttcher, Eva, Matrosovich, Tatyana, Beyerle, Michaela, Klenk, Hans-Dieter, Garten, Wolfgang, Matrosovich, Mikhail
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617224/
https://ncbi.nlm.nih.gov/pubmed/16973594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01118-06
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