Novel Type II Transmembrane Serine Proteases, MSPL and TMPRSS13, Proteolytically Activate Membrane Fusion Activity of the Hemagglutinin of Highly Pathogenic Avian Influenza Viruses and Induce Their Multicycle Replication

Host cellular proteases induce influenza virus entry into cells by cleaving the viral surface envelope glycoprotein hemagglutinin (HA). However, details on the cellular proteases involved in this event are not fully available. We report here that ubiquitous type II transmembrane serine proteases, MS...

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Detalhes bibliográficos
Main Authors: Okumura, Yuushi, Takahashi, Etsuhisa, Yano, Mihiro, Ohuchi, Masanobu, Daidoji, Tomo, Nakaya, Takaaki, Böttcher, Eva, Garten, Wolfgang, Klenk, Hans-Dieter, Kido, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863848/
https://ncbi.nlm.nih.gov/pubmed/20219906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02605-09
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