Novel Type II Transmembrane Serine Proteases, MSPL and TMPRSS13, Proteolytically Activate Membrane Fusion Activity of the Hemagglutinin of Highly Pathogenic Avian Influenza Viruses and Induce Their Multicycle Replication

Host cellular proteases induce influenza virus entry into cells by cleaving the viral surface envelope glycoprotein hemagglutinin (HA). However, details on the cellular proteases involved in this event are not fully available. We report here that ubiquitous type II transmembrane serine proteases, MS...

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Bibliografiska uppgifter
Huvudupphovsmän: Okumura, Yuushi, Takahashi, Etsuhisa, Yano, Mihiro, Ohuchi, Masanobu, Daidoji, Tomo, Nakaya, Takaaki, Böttcher, Eva, Garten, Wolfgang, Klenk, Hans-Dieter, Kido, Hiroshi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2010
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863848/
https://ncbi.nlm.nih.gov/pubmed/20219906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02605-09
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