BRG1, the ATPase subunit of SWI/SNF chromatin remodeling complex, interacts with HDAC2 to modulate telomerase expression in human cancer cells

Telomerase is often upregulated during initiation and/or progression of human tumors, suggesting that repression of telomerase might inhibit cancer growth or progression. Here, we report that BRG1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is a general suppressor of hTERT trans...

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Publicado en:Cell Cycle
Autores principales: Wu, Shu, Ge, Yuanlong, Huang, Laiqiang, Liu, Haiying, Xue, Yong, Zhao, Yong
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2014
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Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612678/
https://ncbi.nlm.nih.gov/pubmed/25486475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.946834
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