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Fibroblast Growth Factor Receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice

Although somatic mutations and overexpression of the tyrosine kinase Fibroblast Growth Factor Receptor 3 (FGFR3) are strongly associated with bladder cancer, evidence for their functional involvement in the pathogenesis remains elusive. Previously we showed that activation of Fgfr3 alone is not suff...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Pathol
Κύριοι συγγραφείς: Foth, Mona, Ahmad, Imran, van Rhijn, Bas W. G., van der Kwast, Theodorus, Bergman, Andre M., King, Louise, Ridgway, Rachel, Leung, Hing Y., Fraser, Sioban, Sansom, Owen J., Iwata, Tomoko
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612374/
https://ncbi.nlm.nih.gov/pubmed/24519156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4334
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