Fibroblast Growth Factor Receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice

Although somatic mutations and overexpression of the tyrosine kinase Fibroblast Growth Factor Receptor 3 (FGFR3) are strongly associated with bladder cancer, evidence for their functional involvement in the pathogenesis remains elusive. Previously we showed that activation of Fgfr3 alone is not suff...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Foth, Mona, Ahmad, Imran, van Rhijn, Bas W. G., van der Kwast, Theodorus, Bergman, Andre M., King, Louise, Ridgway, Rachel, Leung, Hing Y., Fraser, Sioban, Sansom, Owen J., Iwata, Tomoko
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612374/
https://ncbi.nlm.nih.gov/pubmed/24519156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4334
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