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The G1 phase E3 ubiquitin ligase TRUSS that gets deregulated in human cancers is a novel substrate of the S-phase E3 ubiquitin ligase Skp2

E3 ubiquitin ligases have been implicated in the ubiquitination and proteasome-mediated degradation of several key regulators of cell cycle. Owing to their pleotropic behavior, E3 ubiquitin ligases are tightly regulated both at transcriptional and post-translational levels. The E3 ubiquitin ligase T...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Cycle
Hauptverfasser: Jamal, Azfar, Swarnalatha, Manickavinayaham, Sultana, Sarwat, Joshi, Prashant, Panda, Subrat K., Kumar, Vijay
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612110/
https://ncbi.nlm.nih.gov/pubmed/26038816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1056946
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