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DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease

In the brain, programmed cell death (PCD) serves to adjust the numbers of the different types of neurons during development, and its pathological reactivation in the adult leads to neurodegeneration. Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) is a pleiotropic kinase i...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Barallobre, M J, Perier, C, Bové, J, Laguna, A, Delabar, J M, Vila, M, Arbonés, M L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611726/
https://ncbi.nlm.nih.gov/pubmed/24922073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.253
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