DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease

In the brain, programmed cell death (PCD) serves to adjust the numbers of the different types of neurons during development, and its pathological reactivation in the adult leads to neurodegeneration. Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) is a pleiotropic kinase i...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Barallobre, M J, Perier, C, Bové, J, Laguna, A, Delabar, J M, Vila, M, Arbonés, M L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611726/
https://ncbi.nlm.nih.gov/pubmed/24922073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.253
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