Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening

STAT3 regulates a variety of genes involved with cell proliferation, differentiation, apoptosis, angiogenesis, metastasis, inflammation, and immunity. The purpose of this study was to apply molecular docking techniques to identify STAT3 inhibitors from a database of over 90 000 natural product and n...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Liu, L-J, Leung, K-H, Chan, D S-H, Wang, Y-T, Ma, D-L, Leung, C-H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611723/
https://ncbi.nlm.nih.gov/pubmed/24922077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.250
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