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Hit identification of IKKβ natural product inhibitor
BACKGROUND: The nuclear factor-κB (NF-κB) proteins are a small group of heterodimeric transcription factors that play an important role in regulating the inflammatory, immune, and apoptotic responses. NF-κB activity is suppressed by association with the inhibitor IκB. Aberrant NF-κB signaling activi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583241/ https://ncbi.nlm.nih.gov/pubmed/23294515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-14-3 |
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