Hit identification of IKKβ natural product inhibitor

BACKGROUND: The nuclear factor-κB (NF-κB) proteins are a small group of heterodimeric transcription factors that play an important role in regulating the inflammatory, immune, and apoptotic responses. NF-κB activity is suppressed by association with the inhibitor IκB. Aberrant NF-κB signaling activi...

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Bibliografiske detaljer
Main Authors: Leung, Chung-Hang, Chan, Daniel Shiu-Hin, Li, Ying-Wei, Fong, Wang-Fun, Ma, Dik-Lung
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583241/
https://ncbi.nlm.nih.gov/pubmed/23294515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-14-3
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