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Mistranslation drives the evolution of robustness in TEM-1 β-lactamase

How biological systems such as proteins achieve robustness to ubiquitous perturbations is a fundamental biological question. Such perturbations include errors that introduce phenotypic mutations into nascent proteins during the translation of mRNA. These errors are remarkably frequent. They are also...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Bratulic, Sinisa, Gerber, Florian, Wagner, Andreas
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611672/
https://ncbi.nlm.nih.gov/pubmed/26392536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510071112
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