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Enzyme Efficiency but Not Thermostability Drives Cefotaxime Resistance Evolution in TEM-1 β-Lactamase
A leading intellectual challenge in evolutionary genetics is to identify the specific phenotypes that drive adaptation. Enzymes offer a particularly promising opportunity to pursue this question, because many enzymes’ contributions to organismal fitness depend on a comparatively small number of expe...
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| Publicado no: | Mol Biol Evol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5400381/ https://ncbi.nlm.nih.gov/pubmed/28087769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msx053 |
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