Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration

Parkin and the glial cell line–derived neurotrophic factor (GDNF) receptor RET have both been independently linked to the dopaminergic neuron degeneration that underlies Parkinson’s disease (PD). In the present study, we demonstrate that there is genetic crosstalk between parkin and the receptor tyr...

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Sparad:
Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Meka, Durga Praveen, Müller-Rischart, Anne Kathrin, Nidadavolu, Prakash, Mohammadi, Behnam, Motori, Elisa, Ponna, Srinivas Kumar, Aboutalebi, Helia, Bassal, Mahmoud, Annamneedi, Anil, Finckh, Barbara, Miesbauer, Margit, Rotermund, Natalie, Lohr, Christian, Tatzelt, Jörg, Winklhofer, Konstanze F., Kramer, Edgar R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611569/
https://ncbi.nlm.nih.gov/pubmed/25822020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79300
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