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Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model
Glial cell line-derived neurotrophic factor (GDNF) is a potent survival and regeneration-promoting factor for dopaminergic neurons in cell and animal models of Parkinson disease (PD). GDNF is currently tested in clinical trials on PD patients with so far inconclusive results. The receptor tyrosine k...
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| Veröffentlicht in: | Cell Death Dis |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5059866/ https://ncbi.nlm.nih.gov/pubmed/27607574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.263 |
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