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Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model

Glial cell line-derived neurotrophic factor (GDNF) is a potent survival and regeneration-promoting factor for dopaminergic neurons in cell and animal models of Parkinson disease (PD). GDNF is currently tested in clinical trials on PD patients with so far inconclusive results. The receptor tyrosine k...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Drinkut, Anja, Tillack, Karsten, Meka, Durga P, Schulz, Jorg B, Kügler, Sebastian, Kramer, Edgar R
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059866/
https://ncbi.nlm.nih.gov/pubmed/27607574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.263
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