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Human beta defensin-3 increases CD86 expression on monocytes by activating the ATP-gated channel P2X7()

We previously showed that human beta defensin-3 (hBD-3), an epithelial cell derived antimicrobial peptide, mediates chemotaxis and activation of myeloid cells. Here, we provide evidence that hBD-3 induces the co-stimulatory molecule CD86 on primary human monocytes by a mechanism involving autocrine...

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Vydáno v:J Immunol
Hlavní autoři: Lioi, Anthony B., Ferrari, Brian M., Dubyak, George R., Weinberg, Aaron, Sieg, Scott F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610865/
https://ncbi.nlm.nih.gov/pubmed/26416278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401319
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