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Human beta defensin-3 increases CD86 expression on monocytes by activating the ATP-gated channel P2X7()
We previously showed that human beta defensin-3 (hBD-3), an epithelial cell derived antimicrobial peptide, mediates chemotaxis and activation of myeloid cells. Here, we provide evidence that hBD-3 induces the co-stimulatory molecule CD86 on primary human monocytes by a mechanism involving autocrine...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4610865/ https://ncbi.nlm.nih.gov/pubmed/26416278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401319 |
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