Membrane damage and repair in primary monocytes exposed to human β-defensin-3

Interactions of AMPs with plasma membranes of primary human immune cells are poorly characterized. Analysis of PI exclusion as a measure of membrane integrity indicated that hBD-3 caused membrane perturbations in monocytes but not T or B cells at concentrations typically used to kill bacteria or to...

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Detalhes bibliográficos
Main Authors: Lioi, Anthony B., Reyes Rodriguez, Angel L., Funderburg, Nicholas T., Feng, Zhimin, Weinberg, Aaron, Sieg, Scott F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2012
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050522/
https://ncbi.nlm.nih.gov/pubmed/22837529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0112046
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