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Human β defensin-3 induces chemokines from monocytes and macrophages: diminished activity in cells from HIV-infected persons

Human β defensin-3 (hBD-3) is an antimicrobial peptide with diverse functionality. We investigated the capacity of hBD-3 and, for comparison, Pam3CSK4 and LL-37 to induce co-stimulatory molecules and chemokine expression in monocytes. These stimuli differentially induced CD80 and CD86 on the surface...

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Detalhes bibliográficos
Main Authors: Petrov, Velizar, Funderburg, Nicholas, Weinberg, Aaron, Sieg, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839645/
https://ncbi.nlm.nih.gov/pubmed/23829433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12148
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