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Regulatory and T effector cells have overlapping low to high ranges in TCR affinities for self during demyelinating disease
Having regulatory T cells with the same antigen specificity as the responding conventional T cells is thought to be important in maintaining peripheral tolerance. It has been demonstrated that during experimental autoimmune encephalomyelitis (EAE) there are MOG-specific Tregs that infiltrate into th...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4610855/ https://ncbi.nlm.nih.gov/pubmed/26385521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501464 |
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