Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease

Stroke and vascular dementia are leading causes of morbidity and mortality. Neuroprotective therapies have been proposed but none have proven clinically tolerated and effective. While overstimulation of N-methyl-d-aspartate-type glutamate receptors (NMDARs) is thought to contribute to cerebrovascula...

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מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Takahashi, Hiroto, Xia, Peng, Cui, Jiankun, Talantova, Maria, Bodhinathan, Karthik, Li, Wenjun, Holland, Emily A., Tong, Gary, Piña-Crespo, Juan, Zhang, Dongxian, Nakanishi, Nobuki, Larrick, James W., McKercher, Scott R., Nakamura, Tomohiro, Wang, Yuqiang, Lipton, Stuart A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2015
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609936/
https://ncbi.nlm.nih.gov/pubmed/26477507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14781
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