Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease

Stroke and vascular dementia are leading causes of morbidity and mortality. Neuroprotective therapies have been proposed but none have proven clinically tolerated and effective. While overstimulation of N-methyl-d-aspartate-type glutamate receptors (NMDARs) is thought to contribute to cerebrovascula...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Takahashi, Hiroto, Xia, Peng, Cui, Jiankun, Talantova, Maria, Bodhinathan, Karthik, Li, Wenjun, Holland, Emily A., Tong, Gary, Piña-Crespo, Juan, Zhang, Dongxian, Nakanishi, Nobuki, Larrick, James W., McKercher, Scott R., Nakamura, Tomohiro, Wang, Yuqiang, Lipton, Stuart A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609936/
https://ncbi.nlm.nih.gov/pubmed/26477507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14781
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