Histone Deacetylase 3 Is Required for Efficient T Cell Development

Hdac3 is a key target for Hdac inhibitors that are efficacious in cutaneous T cell lymphoma. Moreover, the regulation of chromatin structure is critical as thymocytes transition from an immature cell with open chromatin to a mature T cell with tightly condensed chromatin. To define the phenotypes co...

Full description

Saved in:
Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Stengel, Kristy R., Zhao, Yue, Klus, Nicholas J., Kaiser, Jonathan F., Gordy, Laura E., Joyce, Sebastian, Hiebert, Scott W., Summers, Alyssa R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609739/
https://ncbi.nlm.nih.gov/pubmed/26324326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00706-15
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items