Histone Deacetylase 3 Is Required for Efficient T Cell Development

Hdac3 is a key target for Hdac inhibitors that are efficacious in cutaneous T cell lymphoma. Moreover, the regulation of chromatin structure is critical as thymocytes transition from an immature cell with open chromatin to a mature T cell with tightly condensed chromatin. To define the phenotypes co...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Stengel, Kristy R., Zhao, Yue, Klus, Nicholas J., Kaiser, Jonathan F., Gordy, Laura E., Joyce, Sebastian, Hiebert, Scott W., Summers, Alyssa R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609739/
https://ncbi.nlm.nih.gov/pubmed/26324326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00706-15
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