Mycobacterium tuberculosis pncA Polymorphisms That Do Not Confer Pyrazinamide Resistance at a Breakpoint Concentration of 100 Micrograms per Milliliter in MGIT

Sequencing of the Mycobacterium tuberculosis pncA gene allows for pyrazinamide susceptibility testing. We summarize data on pncA polymorphisms that do not confer resistance at a susceptibility breakpoint of 100 μg/ml pyrazinamide in MGIT within a cohort of isolates from South Africa and the U.S. Cen...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Whitfield, Michael G., Warren, Robin M., Streicher, Elizabeth M., Sampson, Samantha L., Sirgel, Frik A., van Helden, Paul D., Mercante, Alexandra, Willby, Melisa, Hughes, Kelsey, Birkness, Kris, Morlock, Glenn, van Rie, Annelies, Posey, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609709/
https://ncbi.nlm.nih.gov/pubmed/26292310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01001-15
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